Phase Zero

Your science,
in the weights.

A post-training lab for drug makers. We turn your proprietary data into an open model that reasons like your scientists, and runs in your own cloud.

Your data stays insideYour benchmark decidesYour weights to keep
Example benchmarkMedicinal chemistry · item 412

Compound 7b loses tenfold potency against 7a once the methyl moves to the meta position. Give the most likely reason and cite the assay.

Cites the assay: pass Mechanism plausible: pass Graded by your chemists
Example runRunBenchmark
0Open-weight baseBaseline
1,200Fine-tuned on your ELNFine-tuned
3,400RL on your rubricRL-trained

Before Phase I comes Phase 0: a microdose to learn fast and cheaply. We work the same way. One workflow, one benchmark, proof before scale.

Phase 0, or exploratory IND, studies use doses too small to treat anything. Their only job is to show early whether a candidate is worth the cost of everything that follows.

Four stages,
your model.

DataAbout two weeks
EvaluationTwo to three weeks
Post-trainingFour to six weeks
DeploymentOne to two weeks

First, ELNs, LIMS and assay archives become a clean training set.

Then your scientists’ judgment becomes a private benchmark.

Then fine-tuning and reinforcement learning on open weights, scored against that benchmark at every checkpoint.

Last, it ships to your cloud. The weights are yours.

Deep data,
scarce experts.

Start a pilot
Target rationale
Trained on your target reviews and the literature
Scored on citing the evidence your biologists would
SAR reasoning
Trained on your compound history and assay results
Scored on calling the direction of potency changes
Prior-art landscaping
Trained on your IP team’s past analyses
Scored on finding the art your attorneys found
Based inSan Francisco

We come from post-training at OpenAI and Google DeepMind, and from AI-for-science groups. Now we do that work for one industry.

The long arc: from models that read your science, to models that help do it.

Bring one workflow and the data behind it. We return the same model, reshaped, with the benchmark that proves it. Start your Phase Zero.

A pilot is one dataset, one benchmark and one post-trained model, scoped on a first call. Everything we build stays with you.

Pilot enquiries will open soon.